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57.- "Tianeptine: A new exploratory therapy for asthma" Lechin F, van der Dijs B,
Lechin AE. Chest. (accepted for publication)
56.- "Tianeptine, plasma serotonin and pulmonary hypertension. Lechin F, van der
Dijs B, Lechin AE. The Lancet 361(9351): 87, 2003
55.- "Circulating catecholamines and indoleamines throughout normal wake-sleep
cycle." Lechin F, Pardey-Maldonado B, van der Dijs B, Benaim M, Báez S, Orozco B,
Lechin AE. Psychoneuroendocrinology (In Press)
54.- "Pulmonary hypertension, left ventricular dysfunction and plasma serotonin:
commentary on Deuchar et al.." Lechin F, van der Dijs B, Lechin AE. British
Journal of Pharmacology 137:937:938 2002.
53.- May 21, 2002, November 22, 2005 "Plasma serotonin, pulmonary hypertension and
bronchial asthma." Lechin F, van der Dijs B, Lechin AE. Clinical Science 103:
345-346 2002.
52.- "Airway constriction, asthma severity and serotonin." Lechin F, van der Dijs B,
Lechin AE. Am. J. Respir. Crit. Care Med. (in Press).
51.- "Severe Asthma and plasma serotonin." Lechin F, van der Dijs B, Lechin AE.
Allergy 57: 258-259, 2002.
50.- "Candida Lusitaniae catheter related sepsis in a non-neutropenic adult woman:
case report and review of the literature." Pietrucha-Dilanchan P, Lewis RE, Hussain
A, Lechin AE. Annals of Pharmacotherapy 35(12): 1570-4. 2001.
49.- "The serotonin uptake-enhancing drug tianeptine suppresses asthmatic symptoms
in children. A double-blind crossover placebo-controlled study." Lechin F, van der
Dijs B, Lechin A, Orozco B, Lechin ME, Lechin AE. J. Clin. Pharmacol.
38:918-925, 1998.
48.- "Effects of buspirone on plasma neurotransmitters in healthy subjects." Lechin
F, van der Dijs B, Jara H, Orozco B, Báez S, Benaim M, Lechin M, Lechin AE. J.
Neural Transm. 105 (6/7): 561-573,1998.
47.- "Neuropharmacological treatment of bronchial asthma with an antidepressant
drug: tianeptine. A double-blind crossover placebo-controlled study." Lechin F, van
der Dijs B, Orozco B, Jara H, Rada I, Lechin ME, Lechin AE. Clin. Pharmacol.
Ther. 64: 223-232, 1998.
46.- "Successful neuropharmacological treatment of Myasthenia Gravis. Report of
eight cases." Lechin F, van der Dijs B, Jara H, Báez S, Orozco B, Jahn E, Lechin ME,
Jiménez V, Lechin AE. Res. Comm. Biol. Psychol. Psychiatry 22: 81-94, 1997.
45.- "Plasma neurotransmitter profiles of anxiety, phobia and panic disorder
patients. Acute and chronic effects of buspirone." Lechin F, van der Dijs B, Jara H,
Orozco B, Báez S, Jahn E, Benaim M, Lechin E, Lechin ME, Jiménez V, Lechin AE.
Res. Comm. Biol. Psychol. Psychiatry 22: 95-110, 1997.
44.- "Plasma neurotransmitters, blood pressure and heart rate during
supine-resting, orthostasis and moderate exercise stress test in healthy humans
before and after parasympathetic blockade with atropine." Lechin F, van der Dijs
B, Orozco B, Báez S, Rada I, León G, García Z, Jara H, Lechin AE, Lechin ME.
Res. Comm. Biol. Psychol. Psychiatry 21: 55-72, 1996.
43.- "Plasma neurotransmitters, blood pressure and heart rate during
supine-resting, orthostasis and moderate exercise in severely ill patients: A
model of failing to cope with stress." Lechin F, van der Dijs B, Orozco B, Lechin
AE, Báez S, Lechin ME, Benaim M, Rada I, Acosta E, Arocha L, Jiménez V, León G,
García Z. Psychother. Psychosom. 65: 129-136,1996.
42.- "Increased levels of free-serotonin in plasma of symptomatic asthmatic
patients." Lechin F, van der Dijs B, Orozco B, Lechin ME, Lechin AE. Ann.
Allergy Asthma & Immunol. 77: 245-253, 1996.
41.- "Plasma neurotransmitters, blood pressure and heart rate during supine
resting, orthostasis and moderate exercise conditions in major depressed
patients." Lechin F, van der Dijs B, Orozco B, Lechin ME, Acosta E, Lechin AE,
Báez S, Rada I, Arocha L, León G, García Z. Biol. Psychiat. 38: 166-173,
1995.
40.- "Plasma neurotransmitters, blood pressure and heart rate during
supine-resting, orthostasis and moderate exercise in dysthymic depressed
patients." Lechin F, van der Dijs B, Orozco B, Lechin AE, Báez S, Lechin ME,
Rada I, Acosta E, Arocha L, Jiménez V, León G, García Z. Biol. Psychiat. 37:
884-891, 1995.
39.- "Two types of irritable bowel syndrome: differences in behavior, clinical
signs, distal colon motility and hormonal, neurochemical, metabolic,
physiological and pharmacological profiles." Lechin F, van der Dijs B,
Lechin-Báez S, Lechin A, Orozco B, Lechin M, Rada I, Jara H, Gómez F, Cabrera A,
Jiménez V, Arocha L, León G. Arch. Ven. Farmac. Terap. 12: 105-114,
1994.
38.- "Plasma Catecholamines and Indolamines during attacks and remission on
severe bronchial asthma: possible role of stress." Lechin AE, Varon J, van der
Dijs B, Lechin F. Am. J. Respir. Crit. Care Med. 149: A778, 1994.
37.- "Plasma neurotransmitters, blood pressure and heart rate during rest and
exercise." Lechin AE, Varon J, van der Dijs B, Lechin F (Abstract) Am. J.
Respir. Crit. Care Med. 149: A482, 1994.
36.- "Plasma neurotransmitters and cortisol in chronic illness: role of stress."
Lechin F, van der Dijs B, Lechin AE, Orozco B, Lechin ME, Báez S, Rada I, León G,
Acosta E. J. Med. 25:181-192, 1994.
35.- "Peripheral blood immunological parameters in long term benzodiazepine
users." Lechin F, van der Dijs B, Vitelli-Flores G, Báez S, Lechin ME, Lechin AE,
Orozco B, Rada I, León G, Jiménez V. Clin. Neuropharmacology 17:63-72,
1994.
34.- "Plasma neurotransmitters throughout an oral glucose tolerance test in
essential hypertension." Lechin F, van der Dijs B, Lechin M, Jara H, Lechin A,
Lechin-Báez S, Orozco B, Rada I, Cabrera A, Arocha L, Jiménez V, León G. Clin.
Exp. Hypertension 15: 209-240, 1993.
33.- "Effects of an oral glucose load on plasma neurotransmitters in humans:
involvement of REM sleep?" Lechin F, van der Dijs B, Lechin M, Lechin-Báez S,
Jara H, Lechin A, Orozco B, Rada I, Cabrera A, Jiménez V. Neuropsychobiology 26:
4-11, 1992.
32.- "Dramatic improvement with clonidine of acute pancreatitis showing
raised catecholamines and cortisol plasma levels: case report of five
patients." Lechin F, van der Dijs B, Lechin M, Jara H, Lechin A, Cabrera A, Rada I,
Orozco B, Jiménez V, Valderrama T. J. Med. 23: 339-351, 1992.
31.- "Doxepin therapy for postprandial symptomatic hypoglycemic patients
neurochemical, hormonal and metabolic disturbances." Lechin F, van der Dijs B,
Lechin A, Lechin M, Coll-García E, Jara H, Cabrera A, Jiménez V, Gómez F, Tovar
D, Rada I, Arocha A. Clin. Sci. 80: 373-384, 1991.
30.- "Plasma neurotransmitters and cortisol in duodenal ulcer patients: role of
stress." Lechin F, van der Dijs B, Rada I, Jara H, Lechin A, Cabrera A, Lechin M,
Jiménez V, Gómez F, Villa S, Acosta A, Arocha L. Dig. Dis. Sci. 35:
(11)1313-1319, 1990.
29.- "Recurrent gastroesophageal symptoms and precordial pain in a
gastrectomized man improved by amytriptyline. Physiologic, metabolic, endocrine,
neurochemical and psychiatric findings." Lechin F, van der Dijs B, Rada I,
Jara H, Lechin M, Cabrera A, Lechin A, Gómez F, Jiménez V, Arocha L,
Valderrama T. J. Med. 20: 407-424, 1989.
28.- "Pimozide therapy for trigeminal neuralgia." Lechin F, van der Dijs B,
Lechin ME, Amat J, Lechin AE, Cabrera A, Gómez F, Acosta E, Arocha L, Villa S,
Jiménez V. Arch. Neurol. 46: 960-963,1989.
27.- "Definite and sustained improvement with pimozide of two patients with
severe trigeminal neuralgia: Some neurochemical, neurophysiological and
neuroendocrinological findings." Lechin F, van der Dijs B, Amat J, Lechin A, Cabrera
A, Lechin ME, Gómez F, Arocha L, Jiménez V. J. Med. 19: 243, 1988.
26.- "Central nervous system circuitry involved in blood pressure regulation."
Lechin F, van der Dijs B, Amat J, Lechin AE. Arch. Ven. Farm. Clin. Terap. 6:
79-101, 1987.
25.- "Effects of clonidine on blood pressure, noradrenaline, cortisol, growth
hormone, and prolactin plasma levels in high and low intestinal tone depressed
patients." Lechin F, van der Dijs B, Jakubowicz D, Camero RE, Villa S, Arocha L,
Lechin A. Neuroendocrinology 41: 156, 1985.
24.- "Treatment of ulcerative colitis with clonidine." Lechin F, van der Dijs B,
Insausti CL, Gómez F, Villa S, Lechin AE, Arocha L, Oramas O. J. Clin.
Pharmacol. 25: 219, 1985.
23.- "Plasma neurotransmitters profile in reactive hypoglycemia." Lechin A, Jara
H, Cabrera A, Villa S, Jiménez V, Guerrero H, van der Dijs B, Lechin F. III
Interamerican Congress of Clinical Pharmacology and Therapeutics and XII
Latin-American Congress of Pharmacology. Arch. Ven. Farm. Clin. Terap. 7, Sup. 1,
Abst. 111, 1988.
22.- "Definite and sustained improvement with pimozide of two patients with severe
trigeminal neuralgia." Lechin F, van der Dijs B, Amat J, Lechin AE, Cabrera A,
Lechin M, Gómez F, Arocha L, Jiménez V. III Interamerican Congress of Clinical
Pharmacology and Therapeutics and XII Latin-American Congress of Pharmacology.
Arch. Ven. Farm. Clin. Terap. 7, Sup. 1, Abst. 108, 1988.
21.- "Definite and sustained improvement with psychoactive drugs of three Crohn's
disease patients." Lechin F, van der Dijs B, Azócar J, Lechin A, Gómez F, Amat J,
Lechin M, Villa S, Báez S, Acosta E, Cabrera A, Vitelli G, Arocha L, Fernandez M,
Mago E. III Interamerican Congress of Clinical Pharmacology and Therapeutics and
XII Latin-American Congress of Pharmacology. Arch. Ven. Farm. Clin. Terap. 7,
Sup. 1, Abst. 89, 1988.
20.- "Plasma neurotransmitters profile in irritable bowel syndrome (IBS) diarrheic
patients." Lechin A, Jara H, Rada I, Villa S, Cabrera A, Jiménez V, van der Dijs B,
Lechin F. III Interamerican Congress of Clinical Pharmacology and Therapeutics and
XII Latin-American Congress of Pharmacology. Arch. Ven. Farm. Clin. Terap. 7,
Sup. 1, Abst. 88, 1988.
19.- "Plasma neurotransmitters profile in duodenal ulcer patients." Jara H, Lechin
A, Rada I, Villa S, Cabrera A, Guerrero H, van der Dijs B, Lechin F. III
Interamerican Congress of Clinical Pharmacology and Therapeutics and XII
Latin-American Congress of Pharmacology. Arch. Ven. Farm. Clin. Terap. 7 Sup. 1,
Abst. 86, 1988.
18.- "Plasma neurotransmitters profile in bronchial asthma." Lechin AE, Villa S,
Jara H, Cabrera A, Jiménez V, van der Dijs B, Lechin F. III Interamerican Congress
of Clinical Pharmacology and Therapeutics and XII Latin-American Congress of
Pharmacology. Arch. Ven. Farm. Clin. Terap. 7, Sup 1, Abst. 10, 1988.
17.- "Adjunctive L-Tryptophan in the treatment of Gilles de la Tourette disease:
model of a proposed neurochemical profile." Lechin F, van der Dijs B, Gómez F,
Lechin ME, Amat J, Lechin AE, Cabrera A, Rodriguez O. III International Congress of
Clinical Pharmacology and Therapeutics and XII Latin-American Congress of
Pharmacology. Arch. Ven. Farm. Clin. Terap. 7, Sup 1, Abst. 8, 1988.
16.- "Plasma neurotransmitters profile in depressive syndromes." Lechin F, van der
Dijs B, Gómez F, Villa S, Cabrera A, Jiménez V, Guerrero H, Lechin AE. III
Interamerican Congress Of Clinical Pharmacology and Therapeutics and XII
Latin-American Congress of Pharmacology. Arch. Ven. Farm. Clin. Terap. 7, sup.1,
Abst. 7, 1988.
15.- "Plasma neurotransmitters in anxiety patients." Gómez F, Lechin AE, Jara H,
Jiménez V, Cabrera A, Guerrero H, van der Dijs B, Lechin F. III Interamerican
Congress of Clinical Pharmacology and Therapeutics and XII Latin-American Congress
of Pharmacology. Arch. Ven. Farm. Clin. Terap. 7, Sup.1, Abst. 4, 1988.
14.- "Plasma neurotransmitters profile in cluster headache." van der Dijs B, Lechin
AE, Villa S, Gómez F, Cabrera A, Jiménez V, Guerrero H, Lechin F. III Interamerican
Congress of Clinical Pharmacology and Therapeutics and XII Latin-American Congress
of Pharmacology. Arch. Ven. Farm. Clin. Terap. 7, Sup 1, Abst.3, 1988.
13.- "Air Medical Transport (Transporte Aeromedico)." Varon J, Fromm RE, Lechin AE.
Interam 1994; 2: 83-6.
12.- "Adult respiratory distress syndrome (ARDS): The Basics." Lechin AE, Varon J.
J Emerg. Med., 1994; 12(1): 63-8.
11.- "Pulmonary complications of HIV infection: Part I." Lechin AE, Varon J.
Hosp. Physician 1993; 29(6): 16-21.
10.- "Pulmonary complications of HIV infection: Part II." Lechin AE, Varon J.
Hosp. Physician 1993; 29(7): 38-40.
9.- "Prediction of nCPAP delivered pressure at altitude (abstract)." Lechin AE,
Fromm R, Varon J, Hirshkowitz M. Chest 1994; 106(Suppl):44S.
8.- "Outcome of patients admitted to a low selective chronic ventilator dependency
unit." Krum W, Lechin AE, Varon J, Reinoso MA. (Abstract). Chest 1994;106(suppl):
142S.
7.- "Fiberoptic bronchoscopy diagnostic yield of various procedures in a training
program." Lechin AE, Varon J, Fromm R, Lam M, Reinoso MA. (Abstract). Chest 1994;
106(Suppl): 54S.
6.- "Learning fiberoptic bronchoscopy: Complication rates." Lechin AE, Varon J,
Fromm R, Goodnight-White S. (Abstract) Am. J. Resp. Crit. Care Med. 1994;
149(Suppl): A624.
5.- "Complications from flexible fiberoptic bronchoscopy in a training program."
Reinoso MA, Lechin AE, Varon J, Wade L. J. Bronchology 1996; 3: 177-181.
4.- "Impending-death and sertaline." Varon J, Lechin AE, Taylor TV. J. Emerg.
Med. 1995; 13(2): 246.
3.- "CPAP machine performance and altitude." Fromm R, Varon J, Lechin AE,
Hirshkowitz M. Chest 1995; 108: 1577-80.
2.- "Hypomagnasemia may reduce airflow limitation." Hauringa AJ, Lechin AE Amer.
Rev. Respir. Dis. 1991, Vol 143 (4) pp: 409.
1.- "The Houston CPAP follow up questionnaire." Hirshkowitz M, Lechin AE. 1994
World Congress on Sleep Apnea.
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